ISSN 2687-0568

Effect of Mg Content on the Structure, Properties and Cytotoxicity of Biodegradable Zn-Fe-Mg Alloys

Authors
E.D. Abdrakhmanova 1, 2 , E.D. Khafizova 1 , M.V. Polenok 1 , R.K. Islamgaliev 1 , Zhen Li 2 , Li Li 2 , Yingru Liang 2 , Meng Zhang 2

1 Ufa University of Science and Technology, Zaki Validi Str., 32, Ufa, 450076, Russia

2 Harbin Engineering University, Nantong Str, No. 145, Harbin Heilongjiang, 150001, China

Rev. Adv. Mater. Technol., 2025, vol. 7, no. 2, pp. 71–78
Abstract

Interest in biodegradable materials for temporary implants based on zinc alloys has been growing annually. The Zn-Fe-Mg alloys are of special interest, as each of its constituent elements is independently considered as biodegradable metallic material. This study presents a comprehensive investigation of the Zn-1%Fe-1%Mg and Zn-1%Fe-5%Mg alloys subjected to high-pressure torsion. A comparative analysis was conducted on the microstructure of the alloys in both as-cast and deformed states, highlighting differences in their phase composition, strength and cytotoxicity. When the magnesium content exceeds 3 wt.%, an additional phase (MgZn2) precipitates alongside the existing Mg2Zn11 phase. Deformation processing of the Zn-1%Fe-1%Mg alloy effectively reduces its brittleness and promotes a more homogeneous distribution of the Mg2Zn11 eutectic throughout the sample volume. In contrast, the Zn-1%Fe-5%Mg alloy retains excessive brittleness even after deformation. The addition of magnesium was found also to accelerate corrosion rates. Nevertheless, the strength, corrosion, and cytotoxicity properties of the Zn-1%Fe-1%Mg alloy meet the requirements for biodegradable materials.

Keywords
Zn; Biodegradable materials; Corrosion; High pressure torsion; Cytotoxicity
Foundings

Ufa University of Science and Technology: PRIORITY-2030

References
Volume 7, No 2
pages 71-78
History
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